Download Advances in Bladder Research by Tung-Tien Sun, Feng-Xia Liang, Xue-Ru Wu (auth.), Laurence PDF

By Tung-Tien Sun, Feng-Xia Liang, Xue-Ru Wu (auth.), Laurence S. Baskin, Simon W. Hayward (eds.)

The goal of Bladder study Congress, San Francisco, California, April 23-25, 1998, used to be to supply a discussion board for authoritative investigators who're actively thinking about some of the disciplines which outline the prime edges of bladder learn. it will be significant for such investigators to proceed to fulfill frequently for the aim of discussing the most recent advancements of their person fields, to investigate the importance of present examine, to debate new strategies for unresolved difficulties, to significantly evaluation present theories, and to improve new theories and techniques as wanted. the 2 and a part day assembly used to be geared up into 5 part day classes, with each one consultation encompassing certainly one of 5 issues: (1) Epithelial-Mesenchymal Interactions; (2) Ex­ tracellular Matrix and Muscle; (3) Nerves and Pharmacology; (4) an infection and Immunol­ ogy; and (5) Oncology. each one consultation was once brought by means of a moderator via 5 to 6 invited specialist audio system with time for vast interplay from the individuals. late-afternoon poster classes allowed additional interactions among investigators. This publication records the complaints of the Bladder study Congress. it truly is organ­ ized into the 5 half-day periods of the assembly with moderators evaluate and an edited transcription of discussions that each one presentation. i want to thank Sarah Burke and the place of work of constant scientific schooling, USCF; Joanne Hayward, Editorial Assistant; and Miriam Escamilla, Administrative Assis­ tant. i'm hoping you discover this source beneficial. Laurence S. Baskin, M.D.

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54. : Growth kinetics and differentiation in vitro of normal human uroepithelial cells on collagen gel substrates in defined medium. J. , 131: 285, 1987. 55. : Proliferation ofnorrnal and malignant human epithelial cells post irradiation. , 30: 851, 1991. Urothelial Tissue Regulation 29 56. : Nonrandom chromosome losses in stepwise neoplastic transformation in vitro of human uroepithelial cells. ,51: 3323, 199. 57. : Expression of mal is associated with urothelial differentiation in vitro: Identification by differential display reverse-transcriptase polymerase chain reaction.

Chromosomal analysis was performed on urothelial cells at the third and sixth passages. A normal chromosomal complement with no detectable abnormalities was observed by Giemsa staining of metaphase chromosomes. 5 Most of the growth factor biology in human urothelial-associated cells is entirely unknown . This area of study is important in order to further understand the regulatory mechanisms involved with the growth and development of these cells and how it ultimately affects the entire genitourinary system.

Boston, Massachusetts 02115 1. INTRODUCTION The bladder is exposed to a variety of possible injuries from the time the fetus develops. Aside from congenital abnormalities, individuals may also suffer from other disorders such as cancer, trauma, infection, inflammation, iatrogenic injuries or other conditions which may lead to bladder damage or loss, requiring eventual reconstruction. Currently, gastrointestinal segments are used for bladder repair or replacement. ' These include metabolic abnormalities, infection, perforation, urolithiasis, increased mucous production and malignancy.

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