By Ronald Wetzel, Indu Kheterpal
The facility of polypeptides to shape however folded, polymeric buildings similar to amyloids and similar aggregates is being more and more famous as an immense new frontier in protein study. This new quantity of tools in Enzymology besides half C (volume 413) on Amyloid, Prions and different Protein Aggregates proceed within the culture of the 1st quantity (309) in containing particular protocols and methodological insights, supplied by means of leaders within the box, into the newest equipment for investigating the buildings, mechanisms of formation, and organic actions of this crucial type of protein assemblies. * provides designated protocols* comprises troubleshooting information* presents insurance on structural biology, computational tools, and biology
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Extra info for Amyloid, prions, and other protein aggregates, Part B
And Chabry, J. (2004). Purification of the pathological isoform of prion protein (PrPSc or PrP‐res) from transmissible spongiform encephalopathy‐affected brain tissue. In ‘‘Techniques in Prion Research’’ (S. Lehmann and J. ), pp. 16–26. Birkhauser Verlag, Basel. , and Roda, A. (2005). Field‐flow fractionation and biotechnology. Trends Biotechnol. 23, 475–483. , Padgett, M. , Gajdusek, D. , and Gibbs, C. , Jr. (1990). Molecular mass, biochemical composition, and physicochemical behavior of the infectious form of the scrapie precursor protein monomer.
Raymond, L. , Will, R. , Chen, S. , Petersen, R. , Smits, M. , Lansbury, P. , and Caughey, B. (1997). Molecular assessment of the potential transmissibilities of BSE and scrapie to humans. Nature 388, 285–288. , Gajdusek, D. , and Gibbs, C. , Jr. (1973). The clinical characteristics of transmissible Creutzfeldt‐Jakob disease. Brain 96, 1–20. Saborio, G. , and Soto, C. (2001). Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature 411, 810–813. Saborio, G.
Lancet 358, 171–180. , and Zerr, I. (1997). Diagnosis of Creutzfeldt‐Jakob disease and related human spongiform encephalopathies. Biomed. Pharmacother. 51, 381–387. Will, R. , Ironside, J. , Cousens, S. , and Smith, P. G. (1996). A new variant of Creutzfeldt‐Jakob disease in the UK. Lancet 347, 921–925.  Fractionation of Prion Protein Aggregates by Asymmetrical Flow Field‐Flow Fractionation By JAY R. SILVEIRA, ANDREW G. HUGHSON , and BYRON CAUGHEY Abstract Achieving the successful separation and analysis of amyloid and other large protein aggregates can be a difficult proposition.